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Organization

Chai Discovery

Model developer · Research lab · San Francisco, California

Chai Discovery develops AI models for predicting and designing molecular structures and interactions for drug discovery. It released Chai-1, a structure prediction model whose code and weights are now under Apache 2.0, and offers its later Chai-2 design models through an access program rather than as downloads.174Fact reviewed Oct 1, 2026

Last reviewedEntry updated

Using this organization’s offerings

Ownership, delivery, and openness answer different questions. Publicly traded does not mean open source; privately held does not mean closed.

Intended users

Researchers who run Chai-1 locally or in the web server, and life-science organizations seeking access to Chai-2 for antibody and protein design.74Fact reviewed Oct 1, 2026

Hosted and self-hosted access

Chai-1 is installed from PyPI and downloads its weights automatically; a hosted web server is also offered. Chai-2 access is requested through a form.74Fact reviewed Oct 1, 2026

Restrictions and review limits

The chai_lab package requires Linux and a CUDA GPU with bfloat16 support, and its README covers inference only, not training. The terms for Chai-2 access were not reviewed. This profile is not a full product or rights audit.7Fact reviewed Oct 1, 2026

Key facts

Legal name
Chai Discovery, Inc. (as named in the original Chai-1 community license)9
Ownership (separate from openness)
Privately held

Recorded classification; fact-level ownership verification pending.

Legal form
Unknown
Headquarters
San Francisco, California23
Founded
Unknown
Sectors
Science, Open models, Research

What is and isn’t public

An evidence-based summary of what this catalog has documented. It is not a verdict on the organization as a whole.

Chai-1 code and weights are published under Apache 2.0 (see the Chai-1 record). Chai-2 is offered through an access program, and no public weights for later models were found, so Chai's offerings are not uniformly open.78411Fact reviewed Oct 1, 2026

Products

Documented products and how they are delivered. Each row links to the official page.

No hosted model products are recorded for this organization.

Other products

Chai Discovery: other products
ProductKindDocumented delivery and accessReviewed
Chai Lab web server (external site: lab.chaidiscovery.com)OtherBrowser-based service for running Chai-1 without local setup; it requires signing in with an email link.76Oct 1, 2026
Chai-2 access program (external site: chaidiscovery.com)OtherCommercial organizations request access to Chai-2 through a form; Chai says it will offer limited non-commercial access for academics through an early-access form.4Oct 1, 2026

Cataloged artifacts

Records in the Open Models & Tools directory that list this organization as a maintainer or publisher.

Model families (1)

Model releases (1)

Notable documented facts

  • Chai-1 was first released in September 2024 under the Chai Discovery Community License Agreement, which limited use of the code, weights, and outputs to non-commercial purposes and incorporated an acceptable use policy. On November 27, 2024 the repository license was replaced with Apache License 2.0, and the README now states that code and weights are both under Apache 2.0.91078
  • Chai's news page describes a 2026 Pfizer license agreement giving access to its platform, including a model called Chai-3; no public weights for Chai-2 or Chai-3 were found in the pages reviewed.5411

Open positions

Automated job coverage is not configured for this organization.

What this catalog does not know

Unknown means the sources reviewed for this record do not document it. It is not evidence that something does not exist.
  • Founding date: not documented in the sources reviewed.

Have a primary source? How to report a correction.

U.S. eligibility

How this record meets the catalog’s published eligibility policy.

Eligible · basis: U.S. headquarters

Chai Discovery's careers page says its team works in person in San Francisco, California, and its website terms are governed by California law with disputes resolved in San Francisco courts. Its original Chai-1 license names the company as Chai Discovery, Inc. No regulatory filing listing a principal office was reviewed.239

Assessed Oct 1, 2026

Eligibility policy

Sources

  1. 1.
    Chai Discovery (home page) (external site: chaidiscovery.com)

    Chai Discovery · Official page · accessed Oct 1, 2026 · evidence reviewed Oct 1, 2026

  2. 2.
    Careers | Chai Discovery (external site: chaidiscovery.com)

    Chai Discovery · Official page · accessed Oct 1, 2026 · evidence reviewed Oct 1, 2026

  3. 3.
    Chai Discovery Terms of Service (external site: chaidiscovery.com)

    Chai Discovery · Official page · published Jun 30, 2025 · accessed Oct 1, 2026 · evidence reviewed Oct 1, 2026

  4. 4.
    Chai-2 platform and access (Chai Discovery product page) (external site: chaidiscovery.com)

    Chai Discovery · Official page · accessed Oct 1, 2026 · evidence reviewed Oct 1, 2026

  5. 5.
    Research & News | Chai Discovery (external site: chaidiscovery.com)

    Chai Discovery · Official page · accessed Oct 1, 2026 · evidence reviewed Oct 1, 2026

  6. 6.
    Chai Discovery web server sign-in page (external site: lab.chaidiscovery.com)

    Chai Discovery · Official page · accessed Oct 1, 2026 · evidence reviewed Oct 1, 2026

  7. 7.
    chaidiscovery/chai-lab README (external site: raw.githubusercontent.com)

    Chai Discovery · Repository · accessed Oct 1, 2026 · evidence reviewed Oct 1, 2026

  8. 8.
    chaidiscovery/chai-lab LICENSE (Apache License 2.0) (external site: raw.githubusercontent.com)

    Chai Discovery · License · accessed Oct 1, 2026 · evidence reviewed Oct 1, 2026

  9. 9.
    Chai Discovery Community License Agreement (chai-lab LICENSE.md at commit 84849ac) (external site: raw.githubusercontent.com)

    Chai Discovery · License · published Sep 11, 2024 · accessed Oct 1, 2026 · evidence reviewed Oct 1, 2026

  10. 10.
    Commit history for LICENSE.md (chaidiscovery/chai-lab) (external site: github.com)

    Chai Discovery (GitHub) · Repository · accessed Oct 1, 2026 · evidence reviewed Oct 1, 2026

  11. 11.
    Chai Discovery models on Hugging Face (model list API) (external site: huggingface.co)

    Hugging Face · Other · accessed Oct 1, 2026 · evidence reviewed Oct 1, 2026

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