Organization
Boltz
Model developer · Research lab · Developer platform · Boston area, Massachusetts
Boltz is a public benefit corporation that develops AI models for biomolecular structure prediction, binding-affinity estimation, and protein and small-molecule design. Its team started the Boltz models at MIT and founded Boltz PBC, announced in January 2026, which now presents Boltz-1, Boltz-2, and BoltzGen as its open-source models alongside a hosted platform and API.231
Using this organization’s offerings
Intended users
Drug-discovery scientists and teams in academia and industry; the API is also aimed at developers integrating Boltz models into agents and pipelines.29
Hosted and self-hosted access
Boltz-2 can be installed from PyPI and run locally with downloadable checkpoints. Newer models are reached through Boltz Lab or the usage-based Boltz API.12911
Key facts
- Ownership (separate from openness)
- Privately held
Recorded classification; fact-level ownership verification pending.
- Founded
- Unknown
- Sectors
- Science, Open models, Research
What is and isn’t public
Products
Hosted model products
Labeled Hosted product/API — this describes how a documented product is delivered (hosted access). It does not determine whether underlying weights or code are open; assess the specific release and its licenses.
| Product | Kind | Documented delivery and access | Reviewed |
|---|---|---|---|
| Boltz API (external site: boltz.com) | Hosted model API | Usage-based API, with Python and JavaScript SDKs, that serves BoltzMol-1, BoltzProt-1, and Boltz-2 through hosted endpoints.95 | Oct 1, 2026 |
Other products
| Product | Kind | Documented delivery and access | Reviewed |
|---|---|---|---|
| Boltz Lab (external site: boltz.com) | Other | Hosted molecular-design platform with a free monthly prediction allowance on its Professional tier and custom Enterprise plans that include fine-tuning and private deployment options.1011 | Oct 1, 2026 |
Cataloged artifacts
Model families
- Boltz-2Model family
Model releases
- Boltz-2 (boltz2_conf and boltz2_aff checkpoints)Model releaseAvailability: PublicModel-disclosure tier (USASI rubric v0.2): Open-weight
Notable documented facts
- Boltz's founding post says the effort began at MIT and that the founders formed a company to build, maintain, and support products in addition to releasing models. Boltz-2 was released in June 2025 by the Boltz team at MIT Jameel Clinic with Recursion, before the company launch.34
- The open-source Boltz repository that Boltz links from its website is hosted under an individual developer's GitHub account (jwohlwend/boltz), and its MIT LICENSE names three individual developers as copyright holders. Checkpoints are served from a boltz.bio download gateway, with copies on the boltz-community Hugging Face organization.11314
- Boltz's newer BoltzMol-1 and BoltzProt-1 models are offered through Boltz Lab and the Boltz API; the homepage labels only Boltz-2 and BoltzGen as open-source. Its 2026 pharmaceutical collaborations describe access to proprietary Boltz models.156
Open positions
Automated job coverage is not configured for this organization.
What this catalog does not know
- Founding date: not documented in the sources reviewed.
Have a primary source? How to report a correction.
U.S. eligibility
Eligible · basis: U.S. headquarters
Boltz PBC's product and website terms (last updated May 6, 2026) give a Boston, Massachusetts notice address and choose Delaware law, and its 2026 press releases are datelined Cambridge, Massachusetts. The street address in the terms is not reproduced here. No regulatory filing was reviewed.786
Sources
This listing is not an endorsement or a federal approval.