Garyk Brixi
First-listed author of Evo 2, the genome language model from Arc Institute and Stanford
- Researcher training genome language models in the EvoDesign Lab, Stanford University (EvoDesign Lab) and Arc Institute12
Garyk Brixi trains genome language models in the EvoDesign Lab at Stanford and at Arc Institute. Brixi is the first-listed of six authors marked as equal contributors on Evo 2 (Nature, 2026), a model of genomes across all domains of life whose 20B and 40B checkpoints Arc Institute publishes, and a co-author of the original Evo paper (Science, 2024).1354
Research
Brixi describes building AI systems for biology and training genome models, working in the EvoDesign Lab at Stanford and at Arc Institute. Selected work on Brixi's site includes Evo 2 (Nature, 2026), Categorical Jacobian (PNAS, 2024), on how protein language models implicitly learn coevolution, Phalanx (TMLR, 2026), on sliding-window recurrences for biological models, and Minerva (bioRxiv, 2026).1
Brixi is the first-listed author on the Evo 2 paper, one of six authors marked as equal contributors, with Brian Hie and Patrick Hsu among the senior authors. Brixi also co-authored the original Evo paper (Science, 2024) and a 2026 Science paper on generative design of bacteriophages with a genome language model.354
Work
Career timeline
2024
Co-authored the Categorical Jacobian paper in PNAS on coevolution in protein language models.1
Nov 15, 2024
Co-authored the Evo paper published in Science.4
2026
Co-authored Phalanx, on sliding-window recurrences for biological models, in TMLR.1
Mar 4, 2026
Published the Evo 2 paper in Nature as first-listed author.3
Related people
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- Brian HieAlso at Arc Institute
- Alex RivesAI for science
- Abigail SeeAlso from Stanford
- Patrick HsuAlso at Arc Institute
- Ali MadaniAI for science
- Abubakar AbidAlso from Stanford
- Silvana KonermannAlso at Arc Institute
- David WaddenLanguage models
- Albert GuAlso from Stanford
- Hoifung PoonAI for science
- Andrej KarpathyAlso from Stanford
- Jakob UszkoreitLanguage models
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