Gabriele Corso
Co-founder of Boltz and co-author of the open Boltz models and DiffDock for molecular modeling
Gabriele Corso is a co-founder of Boltz, a public benefit corporation that develops open models and agents for AI-driven drug discovery. Corso co-authored the Boltz-1 and Boltz-2 biomolecular models, which began as research at MIT, and is first author of DiffDock, a diffusion model for molecular docking.136
Research
Corso's research applies generative models to molecular structure. DiffDock, posted in October 2022 with Hannes Stärk, Bowen Jing, Regina Barzilay and Tommi Jaakkola, treats docking a small molecule to a protein as a diffusion process over the molecule's position, orientation and torsion angles.6
Boltz models
Boltz PBC
The Boltz models began as research at MIT. In January 2026, Gabriele Corso, Jeremy Wohlwend and Saro Passaro announced that they had founded Boltz as a public benefit corporation to keep releasing open models while building products for drug discovery.1
The launch introduced a preview of Boltz Lab, a platform for running the models and new small-molecule and protein design agents, along with a partnership with Pfizer.2
Work
Boltz-2Open weights
Co-author of Boltz-2 and Boltz-1, open biomolecular interaction models whose code and weights are released under the MIT license.345
DiffDock (external site: arxiv.org)
First author of DiffDock (2022), which frames molecular docking as a generative modeling problem solved with a diffusion process over ligand poses.6
Boltz-2 (boltz2_conf and boltz2_aff checkpoints)Open weights
Second author of the Boltz-2 paper, which the Boltz repository README asks users of the code and models to cite.75
Career timeline
Oct 4, 2022
First-authored the DiffDock paper on diffusion models for molecular docking.6
Nov 20, 2024
Posted the Boltz-1 technical report on democratizing biomolecular interaction modeling.4
Jun 18, 2025
Posted the Boltz-2 technical report on structure and binding affinity prediction.5
Jan 8, 2026
Announced the founding of Boltz as a public benefit corporation with co-founders.12
Jan 8, 2026
Boltz launched a preview of the Boltz Lab platform and its first design agents.2
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